Dosing and administration

Administer CIPRODEX® Otic dosage as follows1:

CIPRODEX® Otic is for use in the ear only. Do not inject CIPRODEX® Otic or use CIPRODEX® Otic in the eye.

4 drops in the ear

4 drops in the ear

2 times a day

2 times a day

7 days

7 days

For exact instructions please see the Prescribing Information.

Advise the patient to read the FDA-approved patient labeling (Patient Information and Instructions for Use).

For Otic Use Only

Advise patients that CIPRODEX® is for otic use only. This product is not approved for use in the eye.

Administration Instructions

Patients should be instructed to warm the bottle in their hand for one to two minutes prior to use and shake well immediately before using.

Allergic Reactions

Advise patients to discontinue use immediately and contact their physician, if rash or allergic reaction occurs.

Avoid Contamination of the Product

Advise patients to avoid contaminating the tip with material from the ear, fingers, or other sources.

Duration of Use

Advise patients that it is very important to use the ear drops for as long as their doctor has instructed, even if the symptoms improve.

Protect from Light

Advise patients to protect the product from light.

Unused Product

Advise patients to discard unused portion after therapy is completed.

CIPRODEX® Otic Dosing

Antibiotic + anti-inflammatory1

CIPRODEX® Otic contains

  • The antibiotic ciprofloxacin to fight against susceptible bacteria in AOE and AOMT

  • The corticosteroid dexamethasone to aid in the resolution of the inflammatory response accompanying bacterial infection


Not actual patients.

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Hypersensitivity Reactions: CIPRODEX® Otic should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity. Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolones.

Potential for Microbial Overgrowth with Prolonged Use: Prolonged use of CIPRODEX® Otic may result in overgrowth of non-susceptible bacteria and fungi. If the infection is not improved after one week of treatment, cultures should be obtained to guide further treatment. If such infections occur, discontinue use and institute alternative therapy.

Continued or Recurrent Otorrhea: If otorrhea persists after a full course of therapy, or if two or more episodes occur within six months, further evaluation is recommended to exclude an underlying condition such as cholesteatoma, foreign body, or a tumor.


The most commonly reported adverse reactions in clinical trials were:


CIPRODEX® Otic is indicated for the treatment of infections caused by susceptible isolates of the designated microorganisms in:


For additional information on CIPRODEX® Otic, please click here for the full Prescribing Information.

References: 1. CIPRODEX [package insert]. Fort Worth, TX: Alcon Laboratories, Inc; 2015.