What is AOE?

ACUTE OTITIS EXTERNA (AOE)

is a diffuse inflammation of the ear canal commonly caused by bacterial infections—commonly known as swimmer's ear1

Ear with illustration of the parts that affected by AOE

COMMON SIGNS AND SYMPTOMS OF AOE1

  • Ear canal inflammation

  • Otalgia (ear pain); pronounced when tugging ear

  • Itching inside the ear

  • Sensation of fullness

  • Otorrhea (drainage)

  • Swelling and redness

  • Temporary hearing loss

  • Tenderness of external ear

Prevalence of AOE in the United States

People Icon

1 in 123

people gets AOE every year1,2

44% Chart Icon

44%

of cases occurred from June to August during 2003—20072

Stetho Icon

2.4 million

ambulatory care center visits each year1,2

44% Chart Icon

44%

of cases occurred from June to August during 2003—20072

53% Chart Icon

53%

of cases are in patients aged 20+ years2

Susceptible bacteria for AOE

98% of AOE cases in North America are bacterial. The most common pathogens are1:

Pseudomonas aeruginosa

Illustration of Pseudomonas aeruginosa

Staphylococcus aureus

Illustration of Staphylococcus aureus

Learn how CIPRODEX® Otic can help your AOE patients

Discover the efficacy
Visual of patients

Not actual patients.

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INDICATIONS AND IMPORTANT SAFETY INFORMATION

CONTRAINDICATIONS

WARNINGS AND PRECAUTIONS

Hypersensitivity Reactions: CIPRODEX® Otic should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity. Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolones.

Potential for Microbial Overgrowth with Prolonged Use: Prolonged use of CIPRODEX® Otic may result in overgrowth of non-susceptible bacteria and fungi. If the infection is not improved after one week of treatment, cultures should be obtained to guide further treatment. If such infections occur, discontinue use and institute alternative therapy.

Continued or Recurrent Otorrhea: If otorrhea persists after a full course of therapy, or if two or more episodes occur within six months, further evaluation is recommended to exclude an underlying condition such as cholesteatoma, foreign body, or a tumor.

ADVERSE REACTIONS

The most commonly reported adverse reactions in clinical trials were:

INDICATIONS and USAGE

CIPRODEX® Otic is indicated for the treatment of infections caused by susceptible isolates of the designated microorganisms in:

DOSAGE

For additional information on CIPRODEX® Otic, please click here for the full Prescribing Information.

References: 1. Rosenfeld RM, Schwartz SR, Cannon CR, et al. Clinical practice guideline: acute otitis externa. Otolaryngol Head Neck Surg. 2014;150(suppl 1):S1-S24. 2. Centers for Disease Control and Prevention. Estimated burden of acute otitis externa—United States, 2003-2007. MMWR Morb Mortal Wkly Rep. 2011;60(19):605-609.